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CSIR WATER > Dr. Fatsi Patrick Senam Kofi

RESEARCH SCIENTIST

Degrees

      BSc – University for Development Studies, Ghana

MSc and Ph.D. – Hiroshima University, Japan 

Active affiliations

–     Council for Scientific and Industrial Research- Water Research Institute (CSIR-WRI)

Dr. Patrick Senam Kofi, Fatsi

Dr. Patrick Senam Kofi Fatsi is a dedicated interdisciplinary life Research Scientist with expertise in molecular biology (including molecular genetics, evolutionary and population genetics, and translational science), epigenomics, microbiology (focusing on nanobacteria, biomineralization, and microbial taxonomy), pathology and immunology (particularly in host-pathogen relationships), antimicrobial resistance (AMR), public and global health, bioinformatics, and biotherapy and biopharmaceutics (such as immunomodulation, phototherapy, phytotherapy, and bacteriophage therapy). He is also skilled in animal handling and care, and microscopy and imaging.

Dr. Fatsi’s current research interests center on antimicrobial resistance, vaccinology, and immunomodulation. He explores the use of bioactive molecules from pathogens—both intracellular and extracellular—to combat antibiotic-resistant bacteria through immunomodulation techniques. His work aims to develop biotherapy-based technologies that could eventually reduce the reliance on chemotherapeutic antimicrobial agents in food-animal production, promoting environmental sustainability and consumer welfare.

His work ethic is characterized by a strong commitment to teamwork and transdisciplinary scientific collaboration, cultural versatility, and a readiness to embrace new challenges.

He is equally an active member of the following professional organizations

  • International Veterinary Vaccinology Network (IVVN)
  • US Animal Vaccinology Research Coordination Network (USAVRCN)
  • European Association of Fish Pathologists (EAFP)
  • American Society of Microbiologists (ASM)
  • World Aquaculture Society (WAS)
  • Japanese Society of Limnology (JSL).

Lists of Publications

  1. Agbeko, E., Fatsi, P. S. K., Appiah, E. K., Johnson-Ashun, M., Birinkorang, S., Donkor, K. K., Ayarika, F. A., Kretsi, E. (2024). Good practices on tilapia hatchery rearing and nursery management techniques. Akosombo, Ghana: CSIR-WRI, ARDEC FAO Training of Fingerlings Producers. Compendium/Manual: 22p.

  2. Agbeko, E., Fatsi, P. S. K., Appiah, E. K., Johnson-Ashun, M., Birinkorang, S., Kretsi, E. (2024). Farmers’ Manual on Tilapia and Catfish Aquaculture Production in Ghana. CSIR-WRI, ARDEC/GAWU-Consultancy: Enhancing Aquaculture Production for Job Creation and Socio-economic Improvement in Ghana: Manual; 23p.

  3. Anani, F. A., Ayarika, F. A., Dankwa, E. T., Donkor, K. Q., Fatsi, P. S. K., Diame, E. A., Opoku, M. (2024). Evaluation of composite nursing of Nile tilapia, Oreochromis niloticus and African catfish, Clarias gariepinus fingerlings in hapa-in-pond system. CSIR-WRI-ARDEC, Akosombo.

  4. Anani, F. A., Donkor, K. K., Ayarika, F. A., Dankwa, E. T., Fatsi, P. S. K., Diame, E. A., Opoku, M. (2024). Growth Performance and Cost-Effectiveness of Composite Nursing of Nile Tilapia (Oreochromis niloticus) and African catfish (Clarias gariepinus) Fingerlings in Hapa-In-Pond systems. Aquaculture Ghana, Book of Abstract 2024.

  5. Fatsi, P. S. K., Johnson-Ashun, M., Bodjagu, P., Asmah R., Oppong, B. B., Addo, A., Kusorgbor, J. K., Ameworwor, M. Y., Agbeko, E. (2024). Innovation for Safe and Sustainable Aquaculture Development (ISSAD): Immunomodulatory and Prophylactic Applications of Bacterial Extracellular Bioactive Molecules (EBMs). Aquaculture Ghana, Book of Abstract 2024.

  6. Anani, F. A., Donkor, K. K., Ayarika, F. A., Dankwa, E. T., Fatsi, P. S. K., Diame, E. A., Opoku, M. (2024). Comparative growth performance and profitability of single and co-nursing of Nile tilapia, Oreochromis niloticus and African catfish, Clarias gariepinus fingerlings in hapa-in-pond system. Aquaculture Ghana 2024 Event, 30th & 31st May, 2024. World Trade Centre, Accra, Ghana. Book of Abstracts.

  7. Anani, F. A., Donkor, K. K., Fatsi, P. S. K., Johnson-Ashun, M., Agbeko, E., Appiah, E. K. (2024). Assessment of Size Distribution of Oreochromis niloticus Fingerlings (Akosombo strain) supplied to Farmers from ARDEC – A Case for Policy Rethinking. Aquaculture Ghana, Book of Abstract 2024.

  8. Appiah, E. K., Fatsi, P. S. K., Magna, E. K, Saito, H., Omura, M., Kawai, K. (2024). Immunomodulatory effects of Mallotus japonicus extract on innate immune responses in Heterotilapia buttikoferi infected with Aeromonas hydrophila. The Microbe. https://doi.org/10.1016/j.microb.2024.100088

  9. Addo, A., Agyakwah S.K., Asmah R., Anani, F. A., Johnson-Ashun, M., Appiah, E. K., Fatsi, P. S. K., Magna, E. K, Saito, H., Kawai, K., Ameworwor, M. Y., Bandoh Oppong, B., Hashem, S., Kusorgbor, J. K., Obeng, A. K., Quansah, L., Saba, C. K. S., Bawah, J., Setufe, S. B., Adu-Nti, F., Quansah, C. R., Osei, L. K., Agbeko, E. (2024) Immunomodulation and Humoral Immune Response in Teleost Immunized with Aeromonas-Derived Antigenic Extracellular Bioactive Molecules. Indian Journal of Microbiology. https://doi.org/10.1007/s12088-024-01254-1

  10. Fatsi, P. S. K., Saito, H., Kawai, K., Hashem, S., Kushida, T., Hamaoka, E. (2024). Genetic relationships between and within some Malawian cichlid genera. Journal of Fish Biology, 1-13. https://doi.org/10.1111/jfb.15848

  11. Asmah R., Mensah E.T-D., Appiah, E. K., Fatsi, P. S. K., Magna, E. K, Adu-Nti, F., Ofosu-Koranteng, F., Kpodo, Z. C., Lente, I. (2024). Preliminary investigation on the occurrence and health risk assessment of antibiotics in cultured tilapia retailed at a commercial outlet in Tema, Ghana. Heliyon, 18;10(6):e28193. https://doi:10.1016/j.heliyon.2024.e28193

  12. Ayarika, F. A., Appiah, E. K., Fatsi, P. S. K., Magna, E. K, Asante, K. A., Abarike, E. D., Kogbe, M., Dabi, M., Sakna, J. K. (2024) Potential Role of Aquaculture Fish to the Recommended Nutritional Intake (RNI) of Children, Adults, Pregnant and Lactating Women in the Asuogyaman Municipality, Ghana. Submitted to the Food Analytical Methods Journal.

  13. Fatsi, P.S.K., Appiah, E.K., Ogasawara, C., Tettey, P.A., Hashem, S., Saito, H. and Kawai, K. (2022). 16S rRNA Gene Sequence Identification of Cultivable – Bacterioplankton Between Ambient Water and Gastrointestinal Tract (GIT) of Resident Teleost. Indian Journal of Microbiology, 62(2), pp.187-194.

  14. Hashem, S., Kawai, K., Fatsi, P. S. K., Kodama, A., Appiah, E. K., Ogasawara, C., and Saito, H. (2022). Genetic differences among the species of genus Aulonocara and related genera of Malawian cichlids. Ecological Genetics and Genomics, 23, 100121.

  15. Fatsi, P. S. K. , Hashem, S., Appiah, E. K., Mensah, E. T. D., Setufe, S. B., Saito, H., & Kawai, K. (2021). Morphological divergence within the largest genetically consistent group of wild Tilapia. Environmental Biology of Fishes , 104(5), 597 -613.104:597-613. https://doi.org/10.1007/s10641-021-01098-4

  16. Hashem S., Koichiro K., Fatsi P. S. K., Kodama A., Hidetoshi S. (2020). Genetic relationships of cichlid fishes from Lake Malawi based on mitochondrial DNA sequences. Limnology, 21(1):151–163. https://doi.org/10.1007/s10201-019-00597-9
  17. Fatsi P. S. K., Hashem, S., Kodama, A., Appiah, E. K., Saito, H., Kawai K. (2020). Population genetics and taxonomic signatures of wild Tilapia in Japan based on mitochondrial DNA control region analysis. Hydrobiologia, 847(6): 1491–1504. https://doi.org/10.1007/s10750-020-04203-3
  18. Fatsi P. S. K., Hashem, S., Appiah, E. K., Mensah E. T-D., Setufe S. B., Saito, H., Kawai K. (2021). Morphological divergence within the largest genetically consistent group of wild Tilapia. Environmental Biology of Fishes, 104(5): 597–613. https://doi.org/10.1007/s10641-021-01098-4
  19. Ogasawara C., Imai T., Kodama A., Fatsi P. S. K., Hashem S., Appiah E. K., Tettey P.A., Hidetoshi S. (2021). Population genetics of the non-native freshwater shrimp Palaemon Sinensis (Sollaud, 1911) in Japan based on mitochondrial 16S rRNA analysis. Aquatic invasions16(4): 710 – 720. https://doi.org/10.3391/ai.2021.16.4.08
  20. Setufe S. B., Amponsah s. K. K., Bilikoni J., Fatsi P. S. K. (2021). A snapshot of the fish community in the Buipe catchment area of the Black Volta River in Ghana. Journal of Fisheries and Coastal Management, 3(1): 10–12. https://doi.org/10.5455/jfcom.20210504062426
  21. Fatsi P. S. K., Appiah E. K., Ogasawara C., Tettey P. A., Hashem S., Hidetoshi S., Kawai K. (2022). 16S rRNA gene sequence identification of cultivable-bacterioplankton between ambient water and gastrointestinal tract (GIT) of a resident teleost. Indian Journal of Microbiology, 62: 187 – 194. https://doi.org/10.1007/s12088-021-00992-w
  22. Appiah E. K., Hashem S., Fatsi P. S. K., Tettey P.A., Hidetoshi S., Omura M., Kawai K. (2022). Antibacterial activity of Mallotus japonicus (L.F.) Müller Argoviensis on the growth of Aeromonas hydrophila, A. salmonicida, Edwasiella tarda, and Vibrio anguillarum. Journal of Applied Microbiology, 132: 298–310. https://doi.org/10.1111/jam.15198
  23. Hashem S., Koichiro K., Fatsi P. S. K., Kodama A., Appiah E. K., Ogasawara C., Hidetoshi S. (2022). Genetic differences among the species of genus Aulonocara and related genera of Malawian cichlids. Ecological Genetics and Genomics, 23: 100121. https://doi.org/10.1016/j.egg.2022.100121
  24. Emmanuel Kaboja Magna E. k., Ofosu-Koranteng F., Mensah E. T-D., Asmah R., Appiah E. K., Fatsi P. S., Adu-Nti F., Kpodo Z. C. (2024). Preliminary investigation on the occurrence and health risk assessment of antibiotics in cultured tilapia retailed at a commercial outlet in Tema, Ghana. Heliyon, 10: e28193. https://doi.org/10.1016/j.heliyon.2024.e28193
  25. Fatsi P. S. K., Kawai K., Asmah R., Oppong B. B., Addo A., Kusorgbor J. K., Obeng A. K., Quansah L., Saba C. K. S., Bawah J., Appiah E. K., Setufe S. B., Hashem S., Hidetoshi S., Adu-Nti F., Ameworwor M. Y., Magna E. K., Johnson-Ashun M., Osei L. K., Agbeko E., Anani F. A., Quansah C. R. (2024). Immunomodulation and humoral immune response in Teleost immunized with Aeromonas-derived antigenic extracellular bioactive molecules. Indian Journal of Microbiology. https://doi.org/10.1007/s12088-024-01254-1
  26. Appiah E. K., Fatsi P. S. K., Magna E. K., Saito H., Omura M., Kawai K. (2024). Immunomodulatory Effects of Mallotus japonicus Extract on Innate Immune Responses in HeteroTilapia buttikoferi Infected with Aeromonas hydrophila. The Microbe. The Microbe. https://doi.org/10.1016/j.microb.2024.100088
  27. Hashem S., Kawai K., Kushida, T., Hamaoka E., Fatsi P. S. K., Saito H. (2024). Genetic relationships between and within some Malawian cichlid genera. Journal of Fish Biology, 1–13. https://doi.org/10.1111/jfb.15848