Dr. Frank Adu-Nti is a Research Scientist at the Biomedical and Public Health Research Unit of the Council for Scientific and Industrial Research – Water Research Institute (CSIR-WRI). I obtained my Bachelor’s degree in Molecular Biology and Biotechnology at the University of Cape Coast in 2008, Master’s degree in Pharmacology in 2013 at the Kwame Nkrumah University of Science and Technology (KNUST) and PhD in Neurobiology in 2021 at Shaanxi Normal University, China.

My research focus bridges areas of neuroscience and pharmacology. I use preclinical animal models to understand the behavioral, neural, and pharmacological factors contributing to animal behavior during development and in disease state and the underlining molecular mechanisms. Other empirical efforts focus on the discovery novel pharmacotherapy approaches from natural products for the treatment of neurodegenerative diseases, neurodevelopmental disorders, mood disorders and other central nervous system diseases. My studies span from molecular and biochemical processes to complex behavioral phenomena, related to the disorders listed above. The approaches include behavioral and molecular neuroscience and neuropharmacology/neurochemistry and I employ a variety of methods, including experimental, neurobehavioral, neuroimaging, neuropathological, and genetic methods in the analyses of behavioral and biological aspects of neurodevelopment, aging and other phenomena.

I have published over 10 peer-reviewed articles in international journals including Frontiers in Pharmacology, CNS Neuroscience and Therapeutics, Behavioral Neuroscience, Life Science, PloS One etc. I serve as a reviewer for Metabolic Brain Disease journal.

List of Publications

Sun, S., Zhou, J., Li, Z., Wu, Y., Wang, H., Zheng, Q., Adu?Nti, F., Juan Fan, Yingfang Tian Progranulin promotes hippocampal neurogenesis and alleviates anxiety?like behavior and cognitive impairment in adult mice subjected to cerebral ischemia. CNS Neurosci Ther  v.28(5); 2022 May. 10.1111/cns.13810

Adu-Nti, F., Xu, G., Wu, J.M., Li, J., Iqbal, J., Ahmed, R., Ma, X-M. Osthole ameliorates estrogen deficiency-induced cognitive deficit in female mice, 2021. Front. Pharmacol. 12:641909 doi: 10.3389/fphar.2021.641909

Iqbal, J., Adu-Nti, F., Wang, X., Qiao, H., Ma, X-M. Sex differences in depression: which animal models mimic it. Behave. Neurosci (2020), 134(3): 248-266. doi: 10.1037/bne0000369

Ghartey-Kwansah, G., Adu-Nti, F., Aboagye, B. et al. Autophagy in the control and pathogenesis of parasitic infections. Cell Biosci 10, 101 (2020). https://doi.org/10.1186/s13578-020-00464-6

Ghartey-Kwansah, G., Aboagye, B., Adu-Nti, F., Opoku, Y.K., Abu, E.K. Clearing or subverting the enemy: Role of autophagy in protozoan infections. Life Sciences 247, 117453 (2020). https://doi.org/10.1016/j.lfs.2020.117453

Adu-Nti F, Ghartey-Kwansha G, Aboagye B (2019) Sex Differences in the Antidepressant Effects of Ketamine in Animal Models of Depression. Int J Depress Anxiety 2:013. doi.org/10.23937/2643-4059/1710013

Tian, Y., Di, Y., Zhang, J., Chen, X., Feng, T., Adu-Nti, F., et al., Angiogenic Gene Profiles in Laser-Microdissected Microvessels and Neurons from Ischemic Penumbra of Rat Brain. J Mol Neurosci 67, 643–653 (2019). https://doi.org/10.1007/s12031-019-01270-7

Ghartey-Kwansah, G., Adu-Nti, F., Aboagye, B., Opoku, Y.K. (2018). Hormetic Effect of Combined Stresses on Drosophila melanogaster Cardiac Performance and Mobility: A Comparative Study. Int. Journal of Molecular Biotechnology, 4(2), 31-42. https://doi.org/10.37628/ijmb.v4i2.356

Ghartey-Kwansah, G., Boampong, J.N., Aboagye, B., Adu-Nti, F., Opoku, Y.K., Quashie, N.B. (2018). The Pervasiveness of ?-Thalassemia in Patients Presenting to Health Facilities in Central and Western Regions of Ghana. Int. Journal of Molecular Biotechnology, 4(2), 14-22.

Ampah KA, Pinho-Nascimento CA, Kerber S, Asare P, De-Graft D, Adu-Nti F, et al. (2016) Limited Genetic Diversity of Hepatitis B Virus in the General Population of the Offin River Valley in Ghana. PLoS ONE 11(6): e0156864.  https://doi.org/10.1371/journal.pone.0156864